Pediatric Cardiology Clinical Trials

Current Pediatric Cardiology Clinical Trials

Study: VTPR-22-07

Study title: Venus Proteus Study

A prospective, multi-center, non-randomized interventional study to evaluate the safety and effectiveness of the VenusP-ValveTM System in patients with native right ventricular outflow tract (RVOT) dysfunction

NCT Number: NCT06010563

Study: 1UG3HL161338-01

Study title: PIVOTAL

Percutaneous Intervention Versus Observational Trial of Arterial Ductus in Low Weight Infants

NCT Number: NCT05547165

Study: MZ_Udenafil-05

Study title: FUEL-2

A 26 week, prospective, multicenter, randomized, double-blinded, placebo-controlled safety and efficacy study of udenafil vs. placebo in adolescent subjects who have had the Fontan procedure. The primary efficacy endpoint will be change from baseline at 26 weeks in peak minute oxygen consumption (VO2 mL/kg/min) as measured by maximal cardiopulmonary exercise test (CPET)

NCT Number: NCT05918211

HEART FAILURE

Study: R44HL167591-01A1

Study title: Emocha ADHERE

A two-group randomized controlled trial to examine the eMocha DOT intervention with pediatric HT recipients.In this population, medication nonadherence remains a primary cause of late acute rejection (LAR) episodes, increased number of hospitalizations, graft failure, and patient mortality.

NCT Number: NCT05732779

Study: BAYER/PHN 21466

Study title: FIORE

A Multicenter, Randomized, Double-blind, Placebo-controlled, Phase 3 Study to Investigate the Efficacy, Safety, and PK/ PD of Finerenone, in Addition to Standard-of-care, in Pediatric Patients, 6 Months to < 18 Years of Age With Heart Failure (HF) and Left Ventricular Systolic Dysfunction (LVSD)

NCT Number: NCT07188805

Study: BAYER/PHN 21467

Study title: FIORELLO

A Phase 3, Single-arm, Open-label Extension Study to Evaluate the Safety of Finerenone in Addition to Standard of Care, in Pediatric Heart Failure Patients, From Birth to 18 Years of Age, With Left Ventricular Systolic Dysfunction (LVSD)

NCT Number: NCT07192952

Study title: PEACE

Predictive Modeling of Acute Rejection in Pediatric Heart Transplant Recipients PEACE