Pediatric Cardiology Clinical Trials
Current Pediatric Cardiology Clinical Trials
Study: VTPR-22-07
Study title: Venus Proteus Study
About the study:
A prospective, multicenter, nonrandomized interventional study evaluating the safety and effectiveness of the VenusP-Valve™ System in patients with native right ventricular outflow tract (RVOT) dysfunction.
NCT Number: NCT06010563
Study: 1UG3HL161338-01
Study title: PIVOTAL
About the study:
Percutaneous Intervention Versus Observational Trial of Arterial Ductus in Low Weight Infants.
NCT Number: NCT05547165
Study: MZ_Udenafil-05
Study title: FUEL-2
About the study:
A 26-week, prospective, multicenter, randomized, double-blind, placebo-controlled study evaluating the safety and effectiveness of udenafil compared with a placebo in adolescents who have had the Fontan procedure. The primary effectiveness endpoint is the change from baseline at 26 weeks in peak oxygen consumption, measured through a maximal cardiopulmonary exercise test.
NCT Number: NCT05918211
Heart Failure
Study: R44HL167591-01A1
Study title: Emocha ADHERE
About the study:
A two-group randomized controlled trial examining the eMocha directly observed therapy intervention in pediatric heart transplant recipients. In this population, medication nonadherence remains a primary cause of late acute rejection episodes, increased hospitalizations, graft failure and patient mortality.
NCT Number: NCT05732779
View Emocha ADHERE study details
Study: BAYER/PHN 21466
Study title: FIORE
About the study:
A multicenter, randomized, double-blind, placebo-controlled Phase 3 study investigating the effectiveness, safety, pharmacokinetics and pharmacodynamics of finerenone, in addition to standard care, in pediatric patients ages 6 months to younger than 18 with heart failure and left ventricular systolic dysfunction.
NCT Number: NCT07188805
Study: BAYER/PHN 21467
Study title: FIORELLO
About the study:
A Phase 3, single-arm, open-label extension study evaluating the safety of finerenone, in addition to standard care, in pediatric patients from birth through age 17 with heart failure and left ventricular systolic dysfunction.
NCT Number: NCT07192952
Study: C4591036
Study title: CAMP
About the study:
A low-intervention cohort study of myocarditis and pericarditis associated with Comirnaty in people younger than 21.
NCT Number: NCT05295290
Study title: Study: PEACE
About the study:
Predictive modeling of acute rejection in pediatric heart transplant recipients.
